|
Study (year) |
Description |
Patients (n)
undergoing TIPSS |
Patient outcome |
Conclusions |
Ref. |
Attwell et al.
(2004) |
Retrospective study
assessing role of TIPSS
and OLT in a single unit |
17 |
14 improved, three died within
1 month. At a mean of 3 years,
eight patients remained well and
four died. Five underwent liver
transplant |
TIPSS can be used as a
bridge to liver transplant
and offers excellent
short-term survival |
【55】 |
Hernàdez-
Guerra et al.
(2004) |
Retrospective study
comparing use of PTFE
(n = 16) and bare metal
(n = 9) stents in BCS |
25 |
At median follow-up of
20.4 months, 16 (87%) bare
metal stents experienced
dysfunction vs 3 (33%) of
PTFE stents |
PTFE stents have a lower
dysfunction rate, lower
number of reinterventions
than bare metal stents and
are preferable |
【43】 |
Kavanagh et al.
(2004) |
Retrospective study of
patients with acute BCS
and liver failure |
5 |
4 underwent TIPSS. 1 died
unexpectedly 2 weeks post-
TIPSS. TIPSS was not possible in
final patient and they underwent
OLT. 80% survival at mean
follow up of 30 months |
Initial TIPSS with OLT for
treatment failures may be
an effective treatment for
BCS |
【56】 |
Rössle et al.
(2004) |
Retrospective analysis of
patients with severe BCS
not responding to
medical therapy who
were selected for TIPSS |
25 |
1-year and 5-year survival rate
without transplantation in all
patients was 93 and 74%,
respectively. Three patients died
and two required OLT |
TIPSS results in an excellent
outcome in patients with
severe fulminant/acute,
subacute and chronic BCS |
【57】 |
Khuroo et al.
(2005) |
Retrospective analysis of
consecutive patients with
BCS receiving TIPSS |
8 |
|
TIPSS recipients had
significantly better survival
than those treated with
medical therapy alone
(p = 0.04) |
【58】 |
Eapen et al.
(2006) |
Retrospective analysis of
61 patients treated with
radiological intervention
alone at a single center |
26 |
1-year and 5-year survival rate of
whole cohort was 94 and 87%,
respectively |
Excellent medium-term
survival for patients in all
categories of disease
severity |
【59】 |
Gandini et al.
(2006) |
Retrospective comparison
of bare (n = 6) or PTFE
(n = 7) stents |
13 |
Mean primary patency duration
was 4.46 months ± 3.40 in bare
metal and 22.29 months ± 8.15
in PTFE group |
PTFE-covered stent-grafts
significantly increased
primary patency rate of
TIPSS in BCS, with reduced
reintervention rate and
prolonged clinical
improvement |
【13】 |
Corso et al.
(2008) |
Retrospective analysis of
TIPSS in BCS where
medical treatment failed |
15 |
TIPSS was very effective in
decreasing the portosystemic
pressure gradient. Two patients
died during follow up (median
follow up 29 months), did not
require OLT |
TIPSS is an effective and
safe treatment for BCS and
may be considered a
valuable alternative to
traditional surgical
portosystemic shunting or
liver transplantation |
【60】 |
Darwish Murad
et al. (2008) |
Retrospective comparison
of patency rates between
bare metal and PTFE
stents |
16 |
Primary patency rate at 2 years
was 12% using bare and 56%
using covered stents (p = 0.09) |
PTFE stents have superior
patency rates in BCS |
【49】 |
Garcai-Pagàn
et al. (2008) |
Retrospective analysis of
outcome and prognostic
factors. Multicenter
European trial |
124 |
1-year and 5-year OLT-free
survival were 88 and 78%,
respectively |
Long-term outcome for
patients with severe BCS
treated with TIPSS is
excellent even in high-risk
patients, suggesting that
TIPSS may improve survival |
【9】 |
Zahn et al.
(2010) |
Retrospective analysis of
patients undergoing
TIPSS (n = 13) or OLT
(n = 4) for BCS |
13 |
Survival in the TIPSS group was
92.3% and 75% in the OLT
group during a median follow-up
of 4 and 11.5 years, respectively |
OLT should be limited to
patients who cannot be
managed by TIPSS |
【61】 |
|
Al-Hilou et al.(2011) |
Retrospective analysis of
patients undergoing
TIPSS (PTFE) between
2001 and 2010 |
30 |
Mean follow-up 38.2 months.
Overall mortality was 23%.
TIPSS thrombosis occurred in
3 patients. 6, 12, 24 and 60
month survival was 96, 90, 86
and 66% respectively. Hepatic
encephalopathy occurred in 13% |
Long-term outcomes
following PTFE covered
TIPSS for BCS are very good
with high rates of primary
patency and clinical
response, good overall
survival and low rates of
hepatic encephalopathy |
【39】 |
