预后因素 Prognostic Parameters in DE-TACE
1. 肿瘤范围 Tumor extent (>25%; >50%): 2), 3), 4)
2. 以前化疗情况 Lines of prior chemotherapy: 1), 6)
3. 体力评分 ECOG performance status: 4)
4. 肝外病变 extrahepatic disease: 1)
5. RECIST反应 RECIST response: 5)
6. 载药微球的吸收 Uptake of contrast added to DE particles: 3)
什么是载药微球的吸收?Uptake of CM/MP(造影剂/微球)
1) Martin 2009; 2) Fiorentini 2012; 3) Huppert 2014
4) Iezzi 2015; 5) Akinwande 2016; 6) Bhutiani 2016
造影剂/载药微球吸收预测局部反应 Uptake predicts local response
肿瘤的范围和血管丰富分级 Tumor Extend and Vascularization
Median time to progression and median survival after TACE in relation to liver tumor involvement and grade of tumor vascularization
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Peter Huppert•Thor stenWenzel•Hubertus Wietholtz Transcatheter Arterial Chemoembolization (TACE) of Colorectal Cancer Liver Metastases by Irinotecan-Eluting Microspheres in a Salvage Patient Population Cardiovasc Intervent Radiol 2014;37:154-64 d-TACE 阳性预测因素 with Positive Predictors:有限的大小,多血管病变和载药微球的吸收程度
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