预后因素 Prognostic Parameters in DE-TACE
1. 肿瘤范围 Tumor extent (>25%; >50%): 2), 3), 4)
2. 以前化疗情况 Lines of prior chemotherapy: 1), 6)
3. 体力评分 ECOG performance status: 4)
4. 肝外病变 extrahepatic disease: 1)
5. RECIST反应 RECIST response: 5)
6. 载药微球的吸收 Uptake of contrast added to DE particles: 3)
什么是载药微球的吸收?Uptake of CM/MP(造影剂/微球)
1) Martin 2009; 2) Fiorentini 2012; 3) Huppert 2014
4) Iezzi 2015; 5) Akinwande 2016; 6) Bhutiani 2016
造影剂/载药微球吸收预测局部反应 Uptake predicts local response
肿瘤的范围和血管丰富分级 Tumor Extend and Vascularization
Median time to progression and median survival after TACE in relation to liver tumor involvement and grade of tumor vascularization
Peter Huppert•Thor stenWenzel•Hubertus Wietholtz Transcatheter Arterial Chemoembolization (TACE) of Colorectal Cancer Liver Metastases by Irinotecan-Eluting Microspheres in a Salvage Patient Population Cardiovasc Intervent Radiol 2014;37:154-64 d-TACE 阳性预测因素 with Positive Predictors:有限的大小,多血管病变和载药微球的吸收程度
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