高达 25% 的患者通常>40 岁; 2/3 有症状
使用 TVS(经阴道超声) 进行诊断,手术/介入栓塞前应MR检查 - 子宫腺肌病亚型和浸润深度对结局有影响
治疗将取决于表现:症状缓解(>40 岁)与不孕症(30 岁左右)
口服前列腺药和左炔诺孕酮释放宫内节育器药物治疗是一线治疗
子宫切除术是不希望保留子宫/生育能力对药物治疗无反应的女性的侵入性治疗金标准
子宫腺肌症病变切除Adenomyomectomy/细胞减灭术 cytoreductive surgery /高能聚焦超声 HIFU
UAE已被证明可安全有效地缓解症状,但缺乏关于妊娠结局的文献: UAE has shown to be safe and affective for symptom relief but literature lacking on pregnancy outcomes: success 80-90%
子宫动脉栓塞被调整为非肿瘤栓塞:比起子宫肌瘤栓塞需要更小的栓塞剂和更进一步的栓塞终点 UAE technique adjusted for non-tumoral embolization: smaller-sized embolics and more aggressive embolization end-point than UFE
患者应该知情一旦治疗失败,7年间面临20%的子宫切除率,比子宫肌瘤栓塞几率大。Patients should be informed on clinical failure rate leading to histerectomy – 20% up to 7 years > than for fibroids
however, UAE for adenmyosis is considered controversial by some authors since recurrence of symptoms has been observed in small case series.
(Goodwin JVIR 1999; Smith JVIR 1999)
nevertheless, some centers have continued UAE, due to persistent requests from patients and gyne’s.(Kitamura AJR 2006; Kim AJR 2007)
未来RCT研究,等待QUEST临床实验结果 Future RCTs – QUESTA trial
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