肝切除术是可切除结直肠癌肝转移的治疗选择 |
Hepatic resection is the treatment of choice for resectable liver metastases from colorectal cancer.
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据解剖学依据和疾病的程度,完全切除必须是可行的;还需要维持肝功能 |
Complete resection must be feasible based on anatomic grounds and the extent of disease; maintenance of adeguate hepatic functio is required |
原发肿瘤必须被切除才能治愈(r0)。不应有不可切除的肝外疾病部位。不建议计划进行去体积切除(小于R0姑息性切除) |
The primary tumor must have been resected for cure (R0). There should be no unresectable extrahepatic sites of disease.0-1l Having a plan for a debulking resection (less than an R0 resection) is not recommended |
可切除转移性疾病和原发肿瘤的患者应在两个部位进行切除达到治愈目的。可通过一次手术或分期切除,依赖于肝切除术或结肠切除术的复杂性、共病疾病、手术暴露和外科医生的专业知识 |
Patients with resectable metastatic disease and a primary tumor in place should have both sites resected with curative intent These car be resected in one operation or as a staged approach, deponding on the complexity of the hepatectomy or colectomy, comorbid diseases, surgical exposure, and surgeon expertise |
当肝转移性疾病因残肝体积不足而不能进行最佳切除时,可以考虑术前采用门静脉栓塞术或分期肝切除术 |
When hepatic metastatic disease is not optimally resectable based on insufficient remnant liver volume, approaches utilizing preoperative portal vein embolization15 or staged liver resection14 can be considered |
消融技术可以单独考虑,也可以考虑与切除联合进行。所有原发疾病部位都需要消融或切除。
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Ablative technigues may be considered alone or in coniunction with resection. All original sites of disease need to be amenable to ablation or resection |
动脉导管治疗,特别是钇90微球选择性内放射治疗,是对高度选择的化疗耐药性难治性疾病和主要肝转移患者的一种选择 |
Arterially directed catheter therapy, and in particular yttrium 90 microsphere selective internal radiation, is an option in highly selected patients with chemotherapy-resistant-refractory disease and with predominant hepatic metastases |
适形外束放射治疗可在高度选择的病例或临床试验中考虑,不应不加区分地用于可能可手术切除的患者 |
Conformal external beam radiation therapy may be considered in highly selected cases or in the setting of a clinical trial and should not be used indiscriminately in patients who are potentially surgically resectable |
对有选择的患者,可考虑重新切除 |
Re-resection can be considered in selected patient |