栓塞导致实性肿瘤微环境中缺氧明显增加Embolization ↑ hypoxic microenvironment of solid tumors
Embolic effect:increases tumor hypoxia
肿瘤缺氧的有害影响: Detrimental effects of Tumor Hypoxia
1. 对化疗的抵抗 Resistance to chemotherapy
2. 促进更多的肿瘤表型 Promotion of more malignant phenotype
3. 细胞凋亡的抑制 Apoptosis inhibition
4. 刺激血管再生 Stimulation of Angiogenesis
5. 导致肿瘤的生长 Cancer growth
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