Chronic pelvic pain (CPP) affects 24% of women worldwide; the cause cannot be identified in 40% despite invasive investigations.
慢性盆腔疼痛(CPP)影响全球24%的女性;尽管进行有创诊断,但40%的妇女无法确定病因。
Dilated, refluxing pelvic veins may be a cause of CPP and treatment by trans-venous occlusion is increasingly performed when gynecological causes are excluded, but is it effective?
扩张,回流盆腔静脉可能是CPP的原因之一,当排除妇科原因时,经静脉闭塞治疗越来越多,但是否有效?
A systematic review of the literature published between 1966 and July 2014 was conducted.
对1966年至2014年7月期间发表的文献进行了系统回顾。
Two authors independently reviewed potential studies according to a set of eligibility criteria, with a third assessor available as an arbiter.
两位作者根据一套资格标准独立审查了潜在的研究,第三位评估者可作为仲裁者。
-The level of evidence assessed using Oxford CEBM guidance
Thirteen studies including 866 women undergoing trans-venous occlusion of pelvic veins for CPP were identified (Level of evidence: one study grade 2b, 12 studies grade 4).
13项研究,包括866名接受经静脉闭塞治疗CPP的妇女(证据水平:一项研究2b级,12项研究4级)。
总共866例
Statistical significant improvements in pelvic pain were reported in nine of the 13 studies.
在13项研究中,有9项研究报告了盆腔疼痛的统计显著改善。
Technical success was reported in 865 of 866 (99.8%)
866份报告中有865份65个项目(99.8%)取得了技术成功。
low complication rates:
并发症发生率低:14例
1. coil migration in 14 women (1.6%) 弹簧栓子迁移(1.6%), 2. abdominal pain in ten women (1.6%), 10例腹痛(1.2%) 3. vein perforation in five (0. 6%) 静脉穿孔5例(0.6) .
4. In a study on varicose veins of the legs, recurrence was seen in 13% of 179 women 5-years following coil embolization.
在一项关于腿部静脉曲张的研究中,在179名5年的妇女中,13%的人在弹簧栓子栓塞后复发。
5. Subjective improvements in pain were seen in all 13 studies after treatment by trans-venous occlusion.
所有13项经静脉闭塞治疗后疼痛的主观改善。
6. All 13 studies were of poor methodological quality.
所有13项研究的方法质量都很差。
7. Complication rates were low and no fatalities occurred.
并发症发生率较低,未发生死亡。
8. Well-designed studies are essential to determine whether pelvic vein incompetence (PVI) is associated with CPP, and to explore whether trans-venous occlusion of PVI improves quality of life for these women.
精心设计的研究对于确定盆腔静脉功能不全(PVI)是否与CPP有关,以及探讨PVI的经静脉阻断是否改善了这些妇女的生活质量至关重要。
“In view of the highly heterogeneous results, pooled success estimates through meta-analysis was not possible or deemed appropriate, as any data synthesis of these results would be likely to provide misleading conclusions about the effectiveness of trans-venous occlusion.
“鉴于结果差异很大,通过元分析得出的综合成功估计数是不可能或被认为是适当的,因为对这些结果的任何数据综合可能会对经静脉闭塞的有效性提供误导性结论。
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