肝切除术后辅助治疗 结直肠癌肝转移新辅助化疗 围手术期肝转移癌化疗 结直肠癌肝转移转化治疗 结直肠癌肝转移姑息治疗
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结直肠癌肝转移切除术后经导管辅助治疗(2)

时间:2021-07-02 14:58来源:www.ynjr.net 作者:杨宁介入医学网
研究二 Modern Systemic Therapy as Adjuvant Therapy after Liver Resection【2】 Between 2001-2005: 125 pts underwent resection of liver mets followed by HAI FUDR +SYS, compared to 125 consecutive pts w



研究二

Modern Systemic Therapy as Adjuvant Therapy after Liver Resection【2】
   

Between 2001-2005: 125 pts underwent resection of liver mets followed by HAI FUDR +SYS, compared to 125 consecutive pts who received Adj Folfox or Folfiri。


研究三:不同化疗方案的结果(HAI+ SYS- Overall Survival by Protocol)


  Total Median OS (95%CI)(years) Median follow up(years)
5 year OS
(95%CI)
HAI + SYS FOLFOX 38  NA  8.4   81% (65%-90%)
HAI + SYS +/- Bev 73 NA  5.3 76% (63%-84%)
HAI + SYS FU/LV 70 6.3 18.8 60% (47%-70%)
HAI + SYS CPT-11 103 6.6  12.2  58% (48%-67%)

 
 
  研究四: 根据Kras基因的生存率( Survival (OS) by KRAS: Liver Resected Patients)

Adjuvant HAI+SYS(MSKCC)【3】
Adjuvant Sys(MD Anderson)【4】
  
Recurrence Free Survival (RFS) by KRAS Liver Resected Patients
Adjuvant HAI+SYS(MSKCC)【3】 Adjuvant Sys(MD Anderson)【4】


  

1. Kemeny NE, Gonen M. Hepatic arterial infusion after liver resection. N Engl J Med. 2005 Feb 17;352(7):734-5.
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