肝动脉灌注的原理(Rationale for Hepatic Arterial Infusion)
• 肝转移病灶肝动脉供血优势,正常肝则主要由门静脉供血( Liver mets perfused by hepatic artery; normal liver by portal vein)
• 某些药物首过肝脏时,由肝脏吸收(Extrated)。减少全身毒性(Some drugs extracted by liver during first pass; less systemic toxicity)
• 肝脏可以是仅有的转移性疾病的位置,转移的进展是楼梯式的(Liver may be only site of metastatic disease; stepwise pattern of metastatic progression)
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