前列腺动脉栓塞病例系列研究(9)

Baseline values of efficacy parameters【3】
Variable	Mean	Standard deviation	Range
IPSS	24.1	6.57	4-35
QoL	4.39	0.95	2-6
IIEF	18.9	8.73	0-34
Qmax (mL/s)	9.19	4.47	1.5-26.8
Prostate vol (mL)	83.5	37.0	24-269
PVR (mL)	102.9	88.9	0.445
PSA (ng/mL)	5.68	6.76	0.14-58.7

技术成功率：至少栓塞一支前列腺动脉250/255(98%)；双侧前列腺栓塞205/250 (82%)；完全栓塞189/205 pts (82.2%)；不完全栓塞16/205 pts (7.8%)；单侧前列腺动脉栓塞51/310 (16.2 %)；技术失败率5/255 (2%)；

操作时间20-185分钟（平均73分钟）；透视时间7-64分钟（平均18分钟）；全部是门诊病人，出院时间3-8小时，220例病人（88%），18小时30例病人（12%）。放射剂量：2121-9766（平均3050 dGy cm²）

结果：

IPSS 下降 12.9 points (P<0.0001)； QoL 下降 2.1 points (P<0.0001)；IIEF 上升 1.1 points (P=0.13)；Qmax 上升 5.0 mL/s (P<0.0001) ；PVR 下降 30.5mL (P=0.002).【3】

How long does it last ?

Late Recurrence：(10/77; 13%)；Mean: 18.1 (range, 5-52 months)；2 lost to follow；引自 Francisco Cesar Carnevale, MD. PhD. GEST 2013

How Long Does it Last?


4 years after uni-PAE	3 months after re-PAE，容积减少31%

1. Pisco JM, Pinheiro LC, Bilhim T, Duarte M, Mendes JR, Oliveira AG. Prostatic arterial embolization to treat benign prostatic hyperplasia. J Vasc Interv Radiol. 2011 Jan;22(1):11-9; （全文）

2.Pisco J, Campos Pinheiro L, Bilhim T, Duarte M, Rio Tinto H, Fernandes L, Vaz Santos V, Oliveira AG. Prostatic arterial embolization for benign prostatic hyperplasia: short- and intermediate-term results. Radiology. 2013 Feb;266(2):668-77.

3. Pisco JM, Rio Tinto H, Campos Pinheiro L, Bilhim T, Duarte M, Fernandes L, Pereira J, Oliveira AG. Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up. Eur Radiol. 2013 Sep;23(9):2561-72.

4. Carnevale FC, da Motta-Leal-Filho JM, Antunes AA, Baroni RH, Marcelino AS, Cerri LM, Yoshinaga EM, Cerri GG, Srougi M. Quality of life and clinical symptom improvement support prostatic artery embolization for patients with acute urinary retention caused by benign prostatic hyperplasia. J Vasc Interv Radiol. 2013 Apr;24(4):535-42. doi: 10.1016/j.jvir.2012.12.019. Epub 2013 Feb 19.

5. Carnevale FC, Antunes AA, da Motta Leal Filho JM, de Oliveira Cerri LM, Baroni RH, Marcelino AS, Freire GC, Moreira AM, Srougi M, Cerri GG. Prostatic artery embolization as a primary treatment for benign prostatic hyperplasia: preliminary results in two patients. Cardiovasc Intervent Radiol. 2010 Apr;33(2):355-61. doi: 10.1007/s00270-009-9727-z. Epub 2009 Nov 12.

6. Carnevale FC, da Motta-Leal-Filho JM, Antunes AA, Baroni RH, Freire GC, Cerri LM, Marcelino AS, Cerri GG, Srougi M. Midterm follow-up after prostate embolization in two patients with benign prostatic hyperplasia. Cardiovasc Intervent Radiol. 2011 Dec;34(6):1330-3.

7. Fernandes L, Rio Tinto H, Pereira J, Duarte M, Bilhim T, Martins Pisco J. Prostatic arterial embolization: post-procedural follow-up. Tech Vasc Interv Radiol. 2012 Dec;15(4):294-9. doi: 10.1053/j.tvir.2012.09.008.

8. Rio Tinto H, Martins Pisco J, Bilhim T, Duarte M, Fernandes L, Pereira J, Campos Pinheiro L.Prostatic artery embolization in the treatment of benign prostatic hyperplasia: short and medium follow-up. Tech Vasc Interv Radiol. 2012 Dec;15(4):290-3. doi: 10.1053/j.tvir.2012.09.005.

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前列腺动脉栓塞病例系列研究(9)