（1）关于产后大出血栓塞治疗文献上最多的是单中心的回顾性研究。目前缺乏药物，外科和血管内介入治疗随机对照研究[1,2]。 （2）系统回顾荟萃分析研究显示[3]：
P=0.06 （3）目前最大一组关于子宫动脉栓塞治疗产后大出血的报告是Touboul等人的N=102[4]； （4）Kirby 等人报告了3个医院的原发性产后出血栓塞的结果，复习了15个文献系列，涉及仅430的病例[5]。 1. J.M. Kirby, J.R. Kachura and D.K. Rajan et al., Arterial embolization for primary postpartum hemorrhage, J Vasc Interv Radiol 20 (2009), pp. 1036–1045. 2. H.A. Mousa and Z. Alfirevic, Treatment for primary postpartum haemorrhage, Cochrane Database Syst Rev (2003) CD003249. 3. .Doumouchtsis SK, Papageorghiou AT, Arulkumaran S. Systematic review of conservative management of postpartum hemorrhage: what to do when medical treatment fails. Obstet Gynecol Surv. 2007 Aug;62(8):540-7.
4. C. Touboul, W. Badiou and J. Saada et al., Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population, PLoS One 3 (2008), p. e3819. |